Diets
Diet is the core treatment for many diseases, including obesity, hypertension, hyperglycemia, and dyslipidemia. Many interventions are beneficial, including replacing harmful fats with health-promoting fats; increasing fiber; increasing phytonutrient content such as flavonoids, polyphenols, and antioxidants from plant-based foods; reducing salt; and restricting calories. The Mediterranean diet is one of the most studied diets and recommends high consumption of extra virgin olive oil, fruits, vegetables, nuts, seeds, legumes, cereals, moderate fish, poultry, dairy, and red wine and lower consumption of eggs, red meat, processed meat, and processed foods. The Mediterranean diet improves blood pressure, lipid profiles, insulin sensitivity, CRP, oxidative stress, atherosclerotic disease, and cognitive function. To reemphasize, a one-size-fits-all diet or macronutrient recommendation is not plausible. The percentage of calories from carbohydrate, fat, and protein needs to be determined on an individual basis. Specific conditions such as chronic kidney disease will benefit from a controlled protein intake, and epilepsy can benefit from a very low-carbohydrate, high-fat ketogenic diet. For years, the field of nutrition has been bombarded with claims of various adjustments in macronutrient ratios having benefit. Nutritionists need to take into account individual disease states and give the patient the most sustainable, realistic plan to improve health. While the ketogenic diet (low-carbohydrate, high-fat) is showing promise for various conditions including epilepsy, cancer, weight loss, type 2 diabetes, metabolic syndrome, dementia, and neurological diseases, the ketogenic diet can be difficult for the average person to sustain. Intermittent fasting (IF) and time-restricted feeding (TRF) may prove to have as important cardiometabolic and neurological benefits as the ketogenic diet and may be appropriate for those who cannot sustain a ketogenic diet. Time-restricted feeding (TRF) may be a feasible alternative to calorie restriction, ketogenic diet, and intermittent fasting when compliance with more restrictive eating regimes is not likely or not recommended. TRF is an eating pattern based around circadian rhythms that occurs within a limited time span (usually 8–12 hours), with a span of 4 hours in between meals with no attention paid to calorie intake.
Integrative and Functional Medical Nutrition Therapy by: Diane Noland, Jeanne A. Drisko, Leigh Wagner
